Rapid care 'cuts baby's HIV risk'
November 21, 2008 00:00:00
Rapid drug treatment of babies with HIV dramatically cuts their risk of death and debilitating disease, international research shows,reports BBC.
The study prompted the World Health Organization to change its guidelines, which had recommended delaying therapy until symptoms became apparent.
It found giving antiretroviral therapy (ART) straight after diagnosis cut the risk of death from Aids by 76pc. The study appears in the New England Journal of Medicine.
The study, of 377 HIV-positive South African babies, found that babies given treatment immediately after they were diagnosed with HIV cut their risk of dying from the infection to just 4pc.
In comparison, the risk of death for those whose treatment was delayed until their levels of key immune system CD4 cells began to fall, or other symptoms emerged, was 16pc.
Immediate treatment also cut the chance of disease progressing measurably by 75pc, from 26pc to 6pc.
The findings were so conclusive that treatment for all babies was re-assessed at the preliminary stage of the trial.
Professor Diana Gibb, from the Medical Research Council clinical trials unit worked on the study.
She said: "We did not expect to see differences so soon between the infants receiving early treatment and those in the group where treatment started only when immunity was falling or symptoms developed."